Kisspeptin-10 — 5mg

Endogenous Neuropeptide & Hypothalamic Regulator | Selective HPGA Axis Activation & LH/FSH Stimulator

Overview:
Kisspeptin-10 is a naturally occurring 10-amino acid cleavage fragment of the Kiss1 gene product and a potent endogenous ligand for the G-protein-coupled receptor GPR54 (KISS1R). Functioning as the primary master regulator of the Hypothalamic-Pituitary-Gonadal Axis (HPGA), Kisspeptin-10 stimulates the pulse release of Gonadotropin-Releasing Hormone (GnRH), which in turn triggers downstream Luteinizing Hormone (LH) and Follicle-Stimulating Hormone (FSH) secretion.

This product is supplied as a sterile lyophilized powder in a 5mg multi-dose vial configuration and requires reconstitution prior to use.

Unlike direct exogenous hormone treatments that suppress natural hypothalamic pathways, Kisspeptin-10 acts at the top of the endocrine cascade to restore and optimize natural hormone signaling.

Because the short 10-amino acid decapeptide sequence contains the active binding core of native Kisspeptin, it offers maximum receptor affinity and rapid activation onset. It is an invaluable research tool for endocrine health, fertility mechanisms, and natural axis recovery studies.

• HPGA Axis Optimization: Triggers endogenous GnRH release to kickstart natural hypothalamic-pituitary signal transmission.
• Stimulates LH & FSH Secretion: Promotes downstream secretion of Luteinizing Hormone and Follicle-Stimulating Hormone.
• Natural Endocrine Restoration: Supports physiological hormone signaling without causing long-term suppression loops.
• Reproductive & Libido Research: Heavily studied for its role in behavioral drive, reproductive system dynamics, and fertility pathways.
• High Chemical Purity: HPLC-verified to ≥98% purity to ensure clean, precise experimental outcomes.

1. Reconstitute using Bacteriostatic Water (BAC).
2. Example: Add 2.0 mL of BAC Water to the 5mg vial for a 2.5 mg/mL (2500 mcg/mL) concentration.
3. Inject BAC water slowly along the inner glass wall—do not squirt directly onto the lyophilized powder cake.
4. Gently swirl (do not shake) until the white powder dissolves completely into a clear liquid.
5. Store reconstituted Kisspeptin-10 in the refrigerator at 2°C – 8°C (36°F – 46°F) and use within 28 days.

For precise reconstitution and dosage calculations, use our Reconstitution Calculator on the website.

Standard Dosage: 100 mcg to 500 mcg per administration based on research protocol parameters.

Timing: Administered via subcutaneous injection 1 to 3 times weekly or as specified by axis stimulation schedules.

Administration Site: Subcutaneous injection into the abdominal area or outer thigh region.

Protocol Duration: Applied in acute or short-to-medium duration cycles depending on target HPGA research goals.

Monitoring & Considerations:

• Common Considerations: Mild temporary injection site redness or light flushing post-injection.
• Monitoring: Evaluate baseline endocrine panels, including LH, FSH, total/free testosterone, and estradiol.
• Contraindications: Hormone-sensitive conditions or active endocrine neoplasms without baseline monitoring.