NAD+ — 500mg

Essential Cellular Coenzyme & Mitochondrial Optimizer | DNA Repair, Metabolic Energy & Anti-Aging Regulator

Overview:
NAD+ (Nicotinamide Adenine Dinucleotide) is a critical coenzyme found in every living cell, responsible for driving mitochondrial ATP energy production, enabling DNA repair through sirtuin activation, and regulating cellular aging pathways. As systemic NAD+ levels naturally decline with age and stress, supplementation supports cellular rejuvenation, cognitive clarity, metabolic efficiency, and accelerated physical recovery.

This product is supplied as a sterile lyophilized powder in a 500mg multi-dose vial configuration and requires reconstitution prior to use.

Direct NAD+ administration bypasses the inefficient digestive pathway of oral precursors, delivering immediate bio-availability at the cellular level.

By refueling mitochondrial pathways, NAD+ restores peak cellular respiration, activates anti-aging sirtuin enzymes (SIRT1–SIRT7), and enhances PARP-mediated DNA repair mechanisms. The high-capacity 500mg vial provides an optimal, cost-effective yield for continuous multi-week research protocols and titration schedules.

• Mitochondrial ATP Energy Boosting: Directly enhances cellular respiration to increase physical vitality and reduce fatigue.
• Cognitive Function & Neuroprotection: Supports mental clarity, focus, and brain health by protecting neurons from oxidative stress.
• Sirtuin Enzyme Activation: Activates longevity pathways linked to DNA maintenance, inflammation control, and cellular aging reversal.
• Metabolic Rate Support: Promotes efficient glucose and lipid utilization for overall metabolic optimization.
• Cellular Repair & Recovery: Accelerates tissue repair following physical exertion, illness, or environmental stress.

1. Reconstitute using Bacteriostatic Water (BAC) or Sterile Water.
2. Example: Add 5.0 mL of BAC Water to the 500mg vial for a 100 mg/mL solution, or 10.0 mL for a 50 mg/mL solution.
3. Inject the water slowly down the inside glass wall—do not squirt directly onto the lyophilized powder.
4. Gently swirl (do not shake) until the powder is fully dissolved into a clear, uniform solution.
5. Store reconstituted NAD+ in the refrigerator at 2°C – 8°C (36°F – 46°F) and protect from direct light exposure.

For precise dose calculations and volume conversions, use our Reconstitution Calculator on the website.

Starting Dosage: 25 mg to 50 mg administered 2 to 3 times weekly (titrating slowly based on tolerance).

Therapeutic Range: 50 mg to 100 mg per administration, up to daily or as required by protocol.

Administration Site: Subcutaneous or intramuscular injection (subcutaneous abdomen injection preferred for gradual absorption).

Protocol Duration: Continuous multi-week cycles (4 to 12 weeks) followed by maintenance phases.

Monitoring & Considerations:

• Common Considerations: Mild subcutaneous sting, temporary warmth, tightness in the chest, or light nausea if injected too rapidly (resolve quickly).
• Administration Tip: Inject slowly over 15–30 seconds to minimize localized stinging or flushing sensations.
• Storage Note: NAD+ in solution is temperature- and light-sensitive; maintain strict refrigeration.